1) Only a single specific primer is required to amplify the template molecule, which can effectively improve the efficiency of adaptor ligation and ensure the full utilization of the template
2) With the YMG™ UMI Adapter & UDI Primer, dual-sided validation can effectively avoid sample data crosstalk; the introduction of UMI adaptor through ligation can reduce background noise, and ctDNA molecules with abundance as low as 0.02% can be stably detected
(3) No double-strand repair is required, reducing the loss of input DNA and increasing the library richness, with a low DNA library input of 1 ng